CEREBRAL AMYLOID ANGIOPATHY Cerebral amyloid angiopathy (CAA), although usually asymptomatic, is an important cause of primary lobar intracerebral hemorrhage (ICH) in the elderly and should be suspected in those with a spontaneous lobar haemorrhage particularly if there is not associated hypertension; it is relatively unusual in individuals younger than 60 years. CAA can occur as a sporadic disorder, with or without associated Alzheimer disease (frequently co-exist), or as a familial syndrome. CAA is characterized by the deposition of congophilic material in small to medium-sized blood vessels of the brain and leptomeninges. This weakens the structure of the vessel wall and…...
